Volume 4 (2017): Issue 1

Gingival bleeding and oral hygiene in women with von Willebrand Disease (VWD): a pilot study

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Stefanie Vanduine
Karen Ridley
Jill Bashutski
Mark Snyder
Corey Powell
Susan Taichman

Abstract

Abstract Introduction

Von Willebrand disease (VWD) is the most common hereditary coagulation abnormality. Individuals with VWD experience increased mucosal bleeding as well as gingival bleeding. Some evidence suggests that gingival bleeding is related to poor oral hygiene for fear of plaque removal methods that may cause bleeding to the gingival tissue. No studies have shown a correlation between VWD and gingival bleeding; however, these studies have not adjusted for possible confounding factors, such as presence of dental plaque, dental care utilisation, and oral hygiene habits.

Aims

To determine the relationship between von Willebrand factor (VWF) levels and the amount of gingival bleeding, when controlling for possible confounding variables.

Methods

This multi-site study included 44 women with VWD who completed a questionnaire to evaluate demographics, oral hygiene habits, perception of own oral health, oral health quality of life, and dental care utilisation. Clinical dental examinations were conducted to determine the presence of plaque and gingival bleeding on six teeth in each individual. Von Willebrand disease type and severity were determined through a medical chart review. Institutional review board (IRB) approval was obtained prior to data collection.

Results

Paired sample t-tests revealed that VWF levels did not significantly affect the amount of gingival bleeding noted (p>0.05) when controlling for presence of plaque. Multiple linear regression models revealed that other factors, such as age and last dental visit (p=0.044), had a larger effect on the amount of gingival bleeding.

Conclusion

In women with VWD, the presence of plaque and dental care utilisation determines gingival bleeding more than the severity of VWD.

Article

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Authors

  • Stefanie Vanduine

    stefmarx@umich.edu
    Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

  • Karen Ridley

    Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

  • Jill Bashutski

    Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

  • Mark Snyder

    Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

  • Corey Powell

    Center for Statistical Consultation and Research, University of Michigan, Ann Arbor, MI, USA

  • Susan Taichman

    Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA